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Gautier Lab, Columbia University


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Selected Publications

  1. Ben-Yehoyada M, Wang LC, Kozekov ID, Rizzo CJ, Gottesman ME, Gautier J. Checkpoint signaling from a single DNA interstrand crosslink. Mol Cell. 2009 Sep 11;35(5):704-15. pmid:19748363. PubMed HubMed [Paperl]
  2. Wang LC, Stone S, Hoatlin ME, Gautier J. Fanconi anemia proteins stabilize replication forks. DNA Repair (Amst). 2008 Sep 8. [Epub ahead of print] pmid:18786657. PubMed HubMed

    [Paperk]

  3. Dupre A, Boyer-Chatenet L, Sattler RM, Modi AP, Lee JH, Nicolette ML, Kopelovich L, Jasin M, Baer R, Paull TT, and Gautier J. A forward chemical genetic screen reveals an inhibitor of the Mre11-Rad50-Nbs1 complex. Nat Chem Biol 2008 Feb; 4(2) 119-25. doi:10.1038/nchembio.63 pmid:18176557. PubMed HubMed

    [Paperj]

  4. Dominguez-Sola D, Ying CY, Grandori C, Ruggiero L, Chen B, Li M, Galloway DA, Gu W, Gautier J, Dalla-Favera R. Non-transcriptional control of DNA replication by c-Myc. Nature. 2007 Jul 26;448(7152):445-51. Epub 2007 Jun 27.pmid:17597761 PubMed HubMed

    [Paperi]

  5. Greenwood J, Gautier J. XLX is an IAP family member regulated by phosphorylation during meiosis. Cell Death Differ. 2007 Mar;14(3):559-67. Epub 2006 Sep 29. PMID: 17008917 PubMed HubMed

    [Paperh]

  6. Dupre A, Boyer-Chatenet L, and Gautier J. Two-step activation of ATM by DNA and the Mre11-Rad50-Nbs1 complex. Nat Struct Mol Biol 2006 May; 13(5) 451-7. doi:10.1038/nsmb1090 pmid:16622404. PubMed HubMed

    [Paperg]

  7. Ying CY, Gautier J. The ATPase activity of MCM2-7 is dispensable for pre-RC assembly but is required for DNA unwinding. EMBO J. 2005 Dec 21;24(24):4334-44. Epub 2005 Nov 24. PMID: 16369567 PubMed HubMed

    [Paperf]

  8. Di Virgilio M, Gautier J. Repair of double-strand breaks by nonhomologous end joining in the absence of Mre11. J Cell Biol. 2005 Dec 5;171(5):765-71. PubMed HubMed

    [Papere]

  9. Yeo W, Gautier J. XNGNR1-dependent neurogenesis mediates early neural cell death. Mech Dev. 2005 May;122(5):635-44. Epub 2005 Jan 8. PubMed HubMed

    [Paperd]

  10. Shechter D, Gautier J. ATM and ATR check in on origins: a dynamic model for origin selection and activation. Cell Cycle. 2005 Feb;4(2):235-8. Epub 2005 Feb 13. PubMed HubMed

    [Paper]

  11. Shechter D, Ying CY, Gautier J. DNA unwinding is an Mcm complex-dependent and ATP hydrolysis-dependent process. J Biol Chem. 2004 Oct 29;279(44):45586-93. Epub 2004 Aug 23. PubMed HubMed

    [Paperc]

  12. Shechter D, Gautier J. MCM proteins and checkpoint kinases get together at the fork. Proc Natl Acad Sci U S A. 2004 Jul 27;101(30):10845-6. Epub 2004 Jul 19. PubMed HubMed

    [Paperb]

  13. Shechter D, Costanzo V, Gautier J. ATR and ATM regulate the timing of DNA replication origin firing. Nat Cell Biol. 2004 Jul;6(7):648-55. Epub 2004 Jun 27. PubMed HubMed

    [Papera]


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